NIH-funded research NIH-funded research

Weight loss and exercise to improve mobility and well-being after stroke in obese veterans

Official title: Enhancing Mobility and Psychosocial function in Obese Veterans following stroke via Weight loss and ExeRcise (EMPOWER)

Funded at Ralph H Johnson VA Medical Center · NIH-11317084 · Data updated 2026-11-12

A study tests whether adding weight loss with or without supervised exercise can help improve physical function and quality of life for obese veterans recovering from stroke.

More Stroke research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRalph H Johnson VA Medical Center
NIH-funded
Lab location1 site (Charleston, United States)
Project startApril 1, 2024
Project endMarch 31, 2028
Funding year2027
NIH project number5I01RX004281-03
Project IDNIH-11317084 on NIH RePORTER

Who could benefit from this research

Could help

Obese veterans who are recovering from stroke and are eligible for weight-loss and rehabilitation programs.

Less likely to help

Stroke survivors who cannot participate in a weight-loss or exercise program or who have contraindications to exercise may not benefit.

What this research studies

This project focuses on veterans who have survived a stroke and are living with obesity. It uses a 15-week, multidisciplinary weight-loss program that may include caloric restriction and optional supervised exercise to see if physical and psychosocial abilities improve during recovery. Participants would engage in coordinated care at the Ralph H Johnson VA Medical Center under an experienced team. The goal is to determine whether weight loss, alone or with exercise, accelerates functional gains after stroke. If successful, findings could guide more effective rehabilitation approaches for this population.

Why it matters

Potential benefit: If successful, the program could lead to better mobility and mood, helping veterans return to daily activities sooner.

How similar studies have gone: Previous weight-loss work shows benefits in healthy adults; this study tests a specific post-stroke, obese veteran population.

Where this research is happening

  • Ralph H Johnson VA Medical Center
    Charleston, United States
    Active

Researchers

  • Principal investigator: Gregory, Chris — Ralph H Johnson VA Medical Center
  • Study coordinator: Gregory, Chris

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.