Helping obese patients with Peripheral Artery Disease maintain their mobility through weight loss

2/2 PROmote weight loss in obese PAD patients to preVEnt mobility loss: The PROVE Trial--DCC

NIH-funded research Wake Forest University Health Sciences · NIH-10889916

This research helps obese patients with Peripheral Artery Disease (PAD) lose weight to keep them moving and active.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-10889916 on NIH RePORTER

What this research studies

For patients living with Peripheral Artery Disease (PAD) who are also obese, losing weight might help prevent further loss of mobility. This research looks at whether a weight loss program can effectively help these patients stay active. We are carefully collecting and managing all the information from participants to ensure the study is well-organized and the results are reliable. The goal is to understand if weight loss can be a key strategy to improve daily life for people with PAD.

Who could benefit from this research

Good fit: Ideal candidates are obese individuals diagnosed with Peripheral Artery Disease who are interested in a weight loss program to improve their mobility.

Not a fit: Patients who are not obese or do not have Peripheral Artery Disease would not be the focus of this specific weight loss approach.

Why it matters

Potential benefit: If successful, this research could show that weight loss is an effective way to preserve mobility for obese individuals living with Peripheral Artery Disease.

How similar studies have performed: While the benefits of weight loss are generally known, this specific approach to prevent mobility loss in obese PAD patients is being rigorously tested in this trial.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cardiovascular Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.