NIH-funded research NIH-funded research

VS4A: A video program to help adolescents with HIV stick to treatment

Official title: VS4A: VITAL Start (Video-Intervention to Inspire Treatment Adherence for Life) for Adolescents, a video intervention to improve retention and adherence to ART among adolescents living with HIV

Funded at Baylor College of Medicine · NIH-11408713 · Data updated 2026-11-12

A video-based program tailored for adolescents with HIV in Malawi aims to improve staying in care and sticking to ART by using engaging videos and conversations.

More Treatment Adherence research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBaylor College of Medicine
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 24, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$749,153
NIH project number5UG1MD019436-04
Project IDNIH-11408713 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents living with HIV in Malawi and their guardians and health care workers involved in their care.

Less likely to help

Teens without access to participating clinics or who do not engage with the Teen Club format may see limited benefit.

What this research studies

This project adapts a proven video intervention for adolescents living with HIV to a new setting, using input from patients, guardians, and health workers. It will test the program in a multisite cluster randomized trial in Malawi, comparing VS4A-enhanced Teen Clubs to standard Teen Clubs. The study looks at whether more teens stay in care and achieve viral suppression at six months, along with how well clinics adopt and implement the intervention. Qualitative work will explore acceptability and feasibility among teens, guardians, and clinicians. If successful, the intervention could be scaled to more sites to improve long-term treatment outcomes for ALHIV.

Why it matters

Potential benefit: If successful, the VS4A program could improve retention in care and viral suppression for adolescents with HIV, leading to better health and fewer HIV-related complications.

How similar studies have gone: Previous video-adherence interventions have shown promise, with potential for improved engagement in care among adolescents in similar settings.

Where this research is happening

  • Baylor College of Medicine
    Houston, United States
    Active

Researchers

  • Principal investigator: Ahmed, Saeed — Baylor College of Medicine
  • Study coordinator: Ahmed, Saeed

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.