NIH-funded research NIH-funded research

VS4A: A video program to help adolescents with HIV stay in care and take their meds

Official title: VS4A: VITAL Start (Video-Intervention to Inspire Treatment Adherence for Life) for Adolescents, a video intervention to improve retention and adherence to ART among adolescents living with HIV

Funded at Baylor College of Medicine · NIH-11425302 · Data updated 2026-11-12

A video-based program designed for adolescents living with HIV in Malawi to help them stay in care and keep their viral load low, tested in a real-world clinic setting.

More Treatment Adherence research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBaylor College of Medicine
NIH-funded
Lab location1 site (Houston, United States)
Project startSeptember 24, 2023
Project endMay 31, 2028
Funding year2026
Award (this year)$367,399
NIH project number3UG1MD019436-04S1
Project IDNIH-11425302 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents living with HIV who are attending clinics in Malawi and have guardians or caregivers involved in their care.

Less likely to help

Adolescents who do not participate in the program or who are in settings where there is limited implementation support may see no benefit.

What this research studies

This project adapts a pediatric/adolescent-focused video intervention called VITAL Start for teens with HIV. It will be tested in a multisite, clinic-based study in Malawi to see if it improves retention in care and adherence to antiretroviral therapy, aiming for viral suppression. The study uses a cluster-randomized design to compare VS4A-enhanced Teen Clubs with standard Teen Clubs, while examining how well facilities adopt and implement the program. Researchers will gather both quantitative outcomes and qualitative feedback from adolescents, guardians, and health workers to refine the approach.

Why it matters

Potential benefit: If successful, the program could help more adolescents with HIV stay in care, take their meds consistently, and achieve better viral suppression.

How similar studies have gone: Prior versions of VS4A or similar video-based adherence interventions have shown promise in improving engagement, with ongoing evaluation in real-world settings.

Where this research is happening

  • Baylor College of Medicine
    Houston, United States
    Active

Researchers

  • Principal investigator: Ahmed, Saeed — Baylor College of Medicine
  • Study coordinator: Ahmed, Saeed

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.