NIH-funded research P01 program project

Vaping in teens: how use develops and its impact on well‑being

Official title: Project 1 - Vaping Behavior, the Emergence of Dependence, and Well-being

Funded at Wake Forest University Health Sciences · NIH-11326314 · Data updated 2026-11-12

A youth-focused study looks at how vaping frequency and dependence form during high school and how it relates to healthy development and well‑being.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences
NIH-funded
Lab location1 site (Winston-Salem, United States)
Project startMay 1, 2023
Project endApril 30, 2028
Funding year2026
Award (this year)$217,710
NIH project number5P01CA269048-04
Project IDNIH-11326314 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adolescents aged 12–20 who vape or are at risk of starting vaping and who are willing to share information about their use and well‑being.

Less likely to help

Teens who do not vape or have no interest in participating may not benefit directly from this study.

What this research studies

This project follows high school students to understand how vaping behavior changes as they age and how dependence might develop. It also explores how nicotine vaping relates to physical, mental, and social well‑being during adolescence. The research combines information on how often and how intensely teens vape with indicators of cognitive, emotional, and social health. The aim is to identify factors that could prevent dependence and support healthier development. The work is designed to inform prevention approaches that can be used in schools and communities.

Why it matters

Potential benefit: If successful, the project could lead to better prevention strategies and resources to keep teens from becoming dependent on nicotine and to support overall well‑being.

How similar studies have gone: Previous research has linked adolescent vaping to dependence and varied well‑being, supporting the potential value of this approach but with ongoing need for comprehensive data.

Where this research is happening

  • Wake Forest University Health Sciences
    Winston-Salem, United States
    Active

Researchers

  • Principal investigator: Donny, Eric Christian — Wake Forest University Health Sciences
  • Study coordinator: Donny, Eric Christian

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.