NIH-funded research U01 cooperative agreement

Vaccine effectiveness in preventing respiratory illness in Washington state (2022–2027)

Official title: RFA-IP-22-004, Evaluating influenza, SARS-CoV-2, and other respiratory virus vaccine effectiveness in prevention of acute illness in Washington state 2022-2027

Funded at Kaiser Foundation Health Plan of Washington · NIH-11379693 · Data updated 2026-11-12

This project tests how well vaccines against flu, COVID-19, and other respiratory viruses protect people in Washington state from getting acutely ill.

More Influenza research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionKaiser Foundation Health Plan of Washington
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 30, 2022
Project endSeptember 29, 2027
Funding year2026
Award (this year)$1,316,666
NIH project number5U01IP001191-05
Project IDNIH-11379693 on NIH RePORTER

Who could benefit from this research

Could help

Adults and children in Washington state who receive vaccines and experience or are at risk for acute respiratory illness may contribute data.

Less likely to help

People who do not contract or report acute respiratory illness or who do not receive vaccination may not directly benefit.

What this research studies

As a current US Flu VE Network site, this project will continue to collect real-world data on how well vaccines prevent acute respiratory illness from influenza, COVID-19, and other respiratory viruses in Washington over the next five years. Researchers will analyze vaccination status, illness episodes, and health outcomes to estimate how vaccines reduce outpatient visits, hospitalizations, and severe illness. The study builds on existing surveillance infrastructure and uses real-world data to inform vaccination policies and public health decisions, with a focus on timely reporting to policymakers. Participants may include patients seeking care for respiratory symptoms and health data will be linked to vaccination records.

Why it matters

Potential benefit: Better, more accurate information on how well vaccines protect people could lead to stronger vaccination recommendations and fewer severe illnesses.

How similar studies have gone: Previous real-world vaccine effectiveness studies have provided actionable insights, supporting the continued surveillance approach used here.

Where this research is happening

  • Kaiser Foundation Health Plan of Washington
    Seattle, United States
    Active

Researchers

  • Principal investigator: Wernli, Karen J — Kaiser Foundation Health Plan of Washington
  • Study coordinator: Wernli, Karen J

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.