Using nutrition to enhance immune function in critically ill patients
Microbiome targeted nutrition to improve immune function during critical illness
This study is looking at how special diets can help boost the immune system and recovery for patients who are very sick, by focusing on the good bacteria in their gut.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11010333 on NIH RePORTER |
What this research studies
This research investigates how targeted nutrition can improve immune function in patients facing critical illness. It focuses on the relationship between the gut microbiome and immune response, particularly how dietary interventions can help restore immune health and bone marrow function. By understanding the impact of nutrition on the microbiome, the study aims to develop strategies that could prevent infections and improve recovery outcomes for critically ill patients. The approach includes analyzing the effects of enteral nutrition on the microbiome and immune system.
Who could benefit from this research
Good fit: Ideal candidates for this research are critically ill patients who are receiving enteral nutrition and may be experiencing immune suppression.
Not a fit: Patients who are not critically ill or those who are not receiving enteral nutrition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved immune function and reduced infection rates in critically ill patients, enhancing their recovery and long-term health outcomes.
How similar studies have performed: While there have been attempts to improve immune function in critically ill patients, this research is exploring a novel approach by focusing on the gut microbiome's role, which has shown promise in preliminary studies.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Chatrizeh, Mona — University of Pittsburgh at Pittsburgh
- Study coordinator: Chatrizeh, Mona
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.