Using engineered bacteria to improve gut health
Development of Engineered Native Bacteria as a Tool for Functional Manipulation of the Gut Microbiome
This study is exploring a new way to use specially designed bacteria to help improve gut health, which could lead to better treatments for people with chronic gut issues.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11092923 on NIH RePORTER |
What this research studies
This research focuses on developing a novel method to manipulate the gut microbiome by using engineered native bacteria. The approach aims to introduce beneficial functions into the gut environment, which could lead to improved health outcomes. By understanding how these bacteria interact with the host, the researchers hope to create more effective therapies for various chronic conditions related to gut health. Patients may benefit from therapies that are tailored to their unique microbiome composition.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals suffering from chronic gastrointestinal disorders or those interested in improving their gut health.
Not a fit: Patients with acute gastrointestinal infections or those who do not have any gut-related health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly improve gut health and overall well-being for patients with chronic gastrointestinal issues.
How similar studies have performed: Previous research has shown promise in manipulating the gut microbiome, but this approach of using engineered native bacteria is relatively novel and untested.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Zarrinpar, Amir — University of California, San Diego
- Study coordinator: Zarrinpar, Amir
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.