Using cooling techniques to protect the spleen during ischemic stroke
Neuroprotection of Remotely Administered Hypothermia on Spleen in Ischemic Stroke
This study is exploring a new way to help protect the brain during a stroke by cooling the spleen from a distance, which might help reduce inflammation and improve recovery for stroke patients.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project ID | NIH-10809221 on NIH RePORTER |
What this research studies
This research investigates a novel approach to protect the brain during ischemic stroke by remotely inducing hypothermia in the spleen. The goal is to reduce inflammation caused by stroke, which can worsen brain damage. By cooling the spleen, the researchers aim to suppress harmful inflammatory responses that occur after a stroke, potentially improving recovery outcomes. The study builds on previous findings that link spleen function and brain recovery in stroke patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have experienced an ischemic stroke and are within the acute phase of treatment.
Not a fit: Patients who have had hemorrhagic strokes or those with chronic conditions that prevent participation in acute interventions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve recovery for stroke patients.
How similar studies have performed: Previous studies have shown promising results in using hypothermia for neuroprotection, indicating that this approach may be viable.
Where this research is happening
Detroit, United States
- Wayne State University — Detroit, United States (Active)
Researchers
- Principal investigator: Ding, Yuchuan — Wayne State University
- Study coordinator: Ding, Yuchuan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.