Using automated machine learning to understand how HIV interacts with addictive drugs

Knowledge-guided automated machine learning methods for modeling the interaction of HIV with addictive drugs

NIH-funded research Cedars-Sinai Medical Center · NIH-11127698

This study is working on new tools to help researchers understand how substance abuse and HIV affect health outcomes, making it easier for everyone to analyze important data and improve care for patients.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCedars-Sinai Medical Center NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-11127698 on NIH RePORTER

What this research studies

This research aims to develop advanced data mining and analytics methods to help the substance abuse and HIV research communities better predict disease outcomes. By utilizing automated machine learning (AutoML), the project seeks to make complex data analysis accessible to all researchers, regardless of their technical expertise. The goal is to analyze multimodal data, including biomarkers related to substance abuse and HIV, to improve clinical decision-making and patient care. The research will leverage an open-source platform called Tree-Based Pipeline Optimization (TPOT) to streamline the process of selecting and optimizing machine learning algorithms for clinical data.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV who also have a history of substance abuse.

Not a fit: Patients who do not have HIV or substance abuse issues may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved prediction of HIV progression and better treatment strategies for patients with substance abuse issues.

How similar studies have performed: Other research has shown success in using machine learning approaches to analyze complex biomedical data, indicating that this method has potential for impactful results.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virusaddictive disorder
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.