Using advanced imaging to identify aggressive prostate cancer
Official title: Multiparametric Photoacoustic Imaging-Based Identification of Aggressive Prostate Cancer
Funded at Worcester Polytechnic Institute · NIH-10694052 · Data updated 2026-11-12
This study is testing a new, gentle imaging method to help find and keep an eye on prostate cancer more accurately, making it easier for men to get the right care without the drawbacks of current tests.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Worcester Polytechnic Institute NIH-funded |
| Lab location | 1 site (Worcester, United States) |
| Project start | September 17, 2019 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $367,933 |
| NIH project number | 5DP5OD028162-05 |
| Project ID | NIH-10694052 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are men who are at risk for prostate cancer or have been diagnosed with prostate abnormalities.
✕Less likely to help
Patients with non-aggressive prostate cancer or those who are not at risk for prostate cancer may not benefit from this research.
What this research studies
This research focuses on developing a new imaging technique called multiparametric photoacoustic (mpPA) sensing to detect and monitor prostate cancer more effectively. By utilizing this non-invasive method, the goal is to improve the identification of prostate tissue abnormalities and assess the aggressiveness of cancer. Current diagnostic methods, such as PSA tests and biopsies, have limitations, including the potential to miss cancerous lesions. This innovative approach aims to provide a more accurate and accessible tool for early detection and ongoing monitoring of prostate cancer.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of aggressive prostate cancer, improving treatment outcomes for patients.
How similar studies have gone: Other research has shown promise in using advanced imaging techniques for cancer detection, indicating that this approach may lead to significant advancements in prostate cancer diagnostics.
Where this research is happening
-
Worcester Polytechnic Institute
Worcester, United States Active
Researchers
- Principal investigator: Zhang, Haichong — Worcester Polytechnic Institute
- Study coordinator: Zhang, Haichong
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AR and RNA-binding in prostate cancer resistance
A cancer research grant exploring how the androgen receptor’s interaction with RNA may drive treatment resistance in prostate cancer, with potential to guide new therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.