Using advanced imaging to detect bleeding cysts in kidney disease
Official title: QSM for detection of hemorrhaging cysts and risk stratification in ADPKD
Funded at Weill Medical Coll of Cornell Univ · NIH-11050780 · Data updated 2026-11-12
This study is testing a new imaging method to help doctors find and understand bleeding cysts in people with autosomal dominant polycystic kidney disease (ADPKD), so they can better predict how these cysts might affect kidney health and treatment outcomes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | January 20, 2025 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $728,513 |
| NIH project number | 1R01DK139336-01A1 |
| Project ID | NIH-11050780 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with autosomal dominant polycystic kidney disease (ADPKD), particularly those with a history of hemorrhagic cysts.
✕Less likely to help
Patients without a diagnosis of ADPKD or those who do not have hemorrhagic cysts may not benefit from this research.
What this research studies
This research focuses on developing a new imaging technique called renal quantitative susceptibility mapping (QSM) to accurately identify and measure hemorrhagic cysts in patients with autosomal dominant polycystic kidney disease (ADPKD). By detecting these cysts, the research aims to provide better risk stratification for patients, helping to predict the decline in kidney function. The study will analyze how these cysts relate to kidney health and the effectiveness of existing treatments. Patients will be monitored to assess the impact of hemorrhagic cysts on their overall kidney function.
Why it matters
Potential benefit: If successful, this research could lead to improved methods for identifying patients at risk of rapid kidney function decline, allowing for more personalized treatment plans.
How similar studies have gone: Previous research has shown that imaging techniques can effectively identify cysts and their impact on kidney disease progression, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Dimov, Alexey — Weill Medical Coll of Cornell Univ
- Study coordinator: Dimov, Alexey
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.