NIH-funded research NIH-funded research

Understanding why malaria persists in Cameroon and how to stop it

Official title: Epidemiological and Entomological Factors Shaping Persistent Malaria Transmission

Funded at University of South Florida · NIH-11518529 · Data updated 2026-11-12

A study in Cameroon will track malaria transmission across different settings to identify which factors keep malaria a problem and how interventions could be made more effective for families and communities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of South Florida
NIH-funded
Lab location1 site (Tampa, United States)
Project startMay 1, 2024
Project endApril 30, 2029
Funding year2026
Award (this year)$203,512
NIH project number3U19AI181593-03S1
Project IDNIH-11518529 on NIH RePORTER

Who could benefit from this research

Could help

Children and families living in Cameroon within varied eco-climatic zones where malaria control is being implemented.

Less likely to help

Participants in areas not experiencing persistent transmission changes or those not engaging with vector-control activities may see limited direct benefit.

What this research studies

This project follows people in diverse Cameroonian communities to see how malaria spreads despite existing controls. Researchers will combine long-term health monitoring with mosquito sampling to uncover which people, places, and mosquito behaviors drive ongoing transmission. They will look at how current interventions affect mosquito populations, parasite spread, and transmission foci over time. The goal is to translate these findings into better, locally tailored malaria control strategies.

Why it matters

Potential benefit: If successful, the research could guide more effective malaria control approaches tailored to Cameroon’s diverse environments, potentially reducing illness in children.

How similar studies have gone: Prior longitudinal and entomological studies have informed malaria control, but this project tests context-specific dynamics in Cameroon.

Where this research is happening

  • University of South Florida
    Tampa, United States
    Active

Researchers

  • Principal investigator: Leke, Rose — University of South Florida
  • Study coordinator: Leke, Rose

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.