NIH-funded research R01 grant

Understanding What Makes Working Memory Training Work for Teens with ADHD or Brain Injury

Official title: Understanding Mediating and Moderating Factors that Determine Transfer of Working Memory Training

Funded at Northeastern University · NIH-11411193 · Data updated 2026-11-12

A study with teens and young adults will test how different ways of training memory and thinking skills work best, especially for those with ADHD or brain injuries.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNortheastern University
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 26, 2016
Project endAugust 31, 2028
Funding year2026
Award (this year)$751,292
NIH project number5R01MH111742-09
Project IDNIH-11411193 on NIH RePORTER

Who could benefit from this research

Could help

Adolescents and young adults (including 0-11 and 21+ years in the dataset annotations) with ADHD or acquired brain injury who are willing to participate in memory training activities.

Less likely to help

Individuals not exposed to cognitive training or who do not meet the study’s age or condition criteria may see no direct benefit.

What this research studies

This project brings together a large group of adolescents to see which features of cognitive training help improve working memory and executive functions. Participants will be randomly assigned to different training formats, including gamified programs, multi-domain training, coaching, and a standard non-gamified approach, using the same set of outcomes. By collecting a big, open dataset, the study aims to clarify what parts of training drive improvement and how reliable those effects are across ages, sex, and ADHD status. The effort is designed to bridge the gap between research findings and real-world practice, with careful attention to rigor and reproducibility.

Why it matters

Potential benefit: If successful, the findings could guide more effective, evidence-based cognitive training options for adolescents and young adults with ADHD or acquired brain injury.

How similar studies have gone: Previous studies show mixed results; this project aims to provide clearer evidence through a large, standardized dataset.

Where this research is happening

  • Northeastern University
    Boston, United States
    Active

Researchers

  • Principal investigator: Seitz, Aaron R — Northeastern University
  • Study coordinator: Seitz, Aaron R

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.