NIH-funded research R01 grant

Ultra-low-power ML brain implants to help manage Alzheimer’s and related disorders

Official title: SCH: Transforming Brain Disorder Management through Ultra-Low-Power ML Implants

Funded at Northeastern University · NIH-11579161 · Data updated 2026-11-12

A project to create a tiny, energy-saving brain-monitoring device with smart software that can help detect and manage Alzheimer’s-related conditions in real time.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNortheastern University
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 7, 2026
Project endJuly 31, 2030
Funding year2026
Award (this year)$313,321
NIH project number1R01NS154768-01
Project IDNIH-11579161 on NIH RePORTER

Who could benefit from this research

Could help

Adults diagnosed with Alzheimer’s disease or related dementias who may benefit from brain-monitoring approaches and wearable/neural interfaces.

Less likely to help

Individuals without Alzheimer’s or related brain disorders are unlikely to benefit from this device-focused approach.

What this research studies

If you or a loved one has Alzheimer’s or related dementia, this project aims to put a small sub-scalp device on your head that uses smart, ultra-low-power machine learning to interpret brain signals as they happen. The team will design new algorithms and a compact hardware system that can work with EEG data without draining battery life, making continuous monitoring more feasible. By addressing differences between individuals’ brain signals, the work seeks to provide reliable, real-time insights that could guide treatments or interventions. The project combines advances in machine learning, circuit design, and systems engineering to create a practical, patient-friendly solution. A proof-of-concept prototype will demonstrate feasibility in real-world conditions for potential clinical use.

Why it matters

Potential benefit: If successful, it could enable real-time monitoring and smarter interventions for people with Alzheimer’s-related conditions, potentially improving symptom management and outcomes.

How similar studies have gone: Previous work shows promise for on-device ML in neural sensing, but the specific ultra-low-power ssEEG and transient ML algorithms are novel.

Where this research is happening

  • Northeastern University
    Boston, United States
    Active

Researchers

  • Principal investigator: Shrivastava, Aatmesh — Northeastern University
  • Study coordinator: Shrivastava, Aatmesh

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.