NIH-funded research R01 grant

Mediators and Modulators of Executive Function Training in Older Adults

Official title: Mediators and Moderators of Executive Function Training in Older Adults

Funded at Northeastern University · NIH-11600335 · Data updated 2026-11-12

A large study to understand what parts of brain-training programs for older adults help or hinder engagement and improvements in thinking skills.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNortheastern University
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 1, 2025
Project endAugust 31, 2030
Funding year2026
Award (this year)$47,248
NIH project number3R01AG089508-02S1
Project IDNIH-11600335 on NIH RePORTER

Who could benefit from this research

Could help

Older adults aged 60 and above, including those at risk for ADRD, who are willing to participate in EF training studies and related data collection.

Less likely to help

Individuals not interested in cognitive training studies or those unable to participate in long-term data collection may not benefit.

What this research studies

This project will gather data from 1,250 older adults to see which ways of delivering executive function training work best and why. It will compare different program ingredients like single vs. multi-component training, gamified elements, and coaching to see how they affect adherence and outcomes. The goal is to make brain-training research more rigorous and practically useful for people at risk of Alzheimer’s disease and related dementias. By collecting a big, standardized dataset, the study aims to identify which training approaches reliably improve cognitive skills and which strategies support ongoing participation.

Why it matters

Potential benefit: If successful, the project could clarify which brain-training approaches truly help older adults maintain or improve thinking abilities and guide future programs.

How similar studies have gone: Previous small studies show mixed results; this large-scale approach seeks clearer, more reliable findings.

Where this research is happening

  • Northeastern University
    Boston, United States
    Active

Researchers

  • Principal investigator: Jaeggi, Susanne M — Northeastern University
  • Study coordinator: Jaeggi, Susanne M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.