Understanding symptoms in children with advanced cancer to guide care
Official title: Defining Symptom Trajectories to Inform Risk-Stratified Approaches to Symptom Management in Children with Advanced Cancer
Funded at University of Wisconsin-Madison · NIH-11272464 · Data updated 2026-11-12
A study to map how symptoms change over time in kids with advanced cancer and use that to tailor better, more proactive symptom care.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | June 1, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $689,340 |
| NIH project number | 1R01CA307143-01 |
| Project ID | NIH-11272464 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children diagnosed with advanced, relapsed, progressed, or refractory cancer who are receiving treatment.
✕Less likely to help
Patients not experiencing advanced cancer or not enrolled in this study may not receive the proposed symptom-management insights.
What this research studies
This project follows children with advanced cancer to track physical and psychological symptoms as their disease and treatments progress. Researchers will collect symptom reports and clinical data over time to identify patterns and factors that influence them. The goal is to translate these insights into risk-stratified symptom management approaches that clinicians can use to anticipate needs and intervene early. The work involves collaborating with families and clinicians across care settings to understand the full symptom experience and its impact on daily life. Results could inform personalized support plans and new intervention timing tailored to each child’s trajectory.
Why it matters
Potential benefit: If successful, the study could lead to more precise and timely symptom management, improving quality of life for children with advanced cancer and reducing distress for families.
How similar studies have gone: Previous work has characterized symptom patterns in early-stage pediatric cancer; this study aims to extend those insights to the advanced-disease population, which is less explored.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Montgomery, Kathleen — University of Wisconsin-Madison
- Study coordinator: Montgomery, Kathleen
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.