Understanding how uterine fluid movement affects contraception
Official title: Dysregulation of uterine fluid movement as a mechanism of contraception
Funded at University of Georgia · NIH-10952672 · Data updated 2026-11-12
This study is looking at how the movement of fluid in the uterus affects pregnancy and contraception, using mice to see how hormones like progesterone help the uterus prepare for an embryo, which could lead to better birth control methods or treatments for infertility in people.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Georgia NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $151,000 |
| NIH project number | 1R03HD115998-01 |
| Project ID | NIH-10952672 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women of reproductive age who are interested in contraception or experiencing difficulties conceiving.
✕Less likely to help
Patients who are not of reproductive age or those who have no interest in contraception or fertility issues may not benefit from this research.
What this research studies
This research investigates the role of uterine fluid movement in the process of contraception and infertility. By studying mouse models, the researchers aim to understand how hormonal signals, particularly progesterone, influence the uterus's ability to accept an embryo for implantation. The study will explore the molecular mechanisms behind uterine receptivity and how blocking this process can serve as an effective contraceptive method. Patients may benefit from insights that could lead to improved contraceptive options or treatments for infertility.
Why it matters
Potential benefit: If successful, this research could lead to new contraceptive methods or treatments for women facing infertility.
How similar studies have gone: While the study explores a novel approach, previous research has shown that hormonal signaling plays a crucial role in reproductive health, indicating potential for success.
Where this research is happening
-
University of Georgia
Athens, United States Active
Researchers
- Principal investigator: Ye, Xiaoqin — University of Georgia
- Study coordinator: Ye, Xiaoqin
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.