Understanding how the brain predicts sounds from movement
Official title: To identify mechanisms of predictive processing across the distributed thalamocortical circuit
Funded at University of Connecticut Storrs · NIH-11239885 · Data updated 2026-11-12
This study is exploring how the brain helps mice predict sounds they make when they move, which is important for understanding how we all process sounds in our daily lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Connecticut Storrs NIH-funded |
| Lab location | 1 site (Storrs-Mansfield, United States) |
| Project start | July 16, 2023 |
| Project end | December 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $249,000 |
| NIH project number | 4R00DC020770-03 |
| Project ID | NIH-11239885 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with auditory processing disorders or related neurological conditions.
✕Less likely to help
Patients with no auditory processing issues or those who do not have neurological conditions may not receive benefit from this research.
What this research studies
This research investigates how the brain anticipates sounds created by its own movements, which is essential for various behaviors. By studying the connections within the thalamocortical circuit, the project aims to uncover the mechanisms that allow the brain to integrate sensory and motor information. Using a specialized mouse model, researchers will map the connections of the auditory thalamus and create an augmented reality environment to observe how mice learn to predict sounds. This approach combines advanced techniques in neuroscience and behavioral analysis to enhance our understanding of auditory processing.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for auditory processing disorders and enhance our understanding of brain function in health and disease.
How similar studies have gone: Other research has shown success in understanding sensory-motor integration, but this specific approach using augmented reality in auditory processing is relatively novel.
Where this research is happening
-
University of Connecticut Storrs
Storrs-Mansfield, United States Active
Researchers
- Principal investigator: Audette, Nicholas J — University of Connecticut Storrs
- Study coordinator: Audette, Nicholas J
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.