Understanding how the amygdala develops during adolescence
Official title: Functional maturation of amygdala circuitry during adolescence
Funded at Children's Research Institute · NIH-11102173 · Data updated 2026-11-12
This study looks at how a part of the brain called the amygdala grows and changes from the teenage years into adulthood, especially focusing on certain young brain cells that might affect behavior and could be linked to mental health issues like autism.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Research Institute NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project start | September 10, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $629,510 |
| NIH project number | 1R56MH133628-01A1 |
| Project ID | NIH-11102173 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adolescents aged 12 to 20, particularly those diagnosed with autism spectrum disorders.
✕Less likely to help
Patients outside the age range of 12 to 20 or those without autism spectrum disorders may not benefit from this research.
What this research studies
This research investigates the development of the amygdala, a brain region crucial for social and emotional behavior, during the transition from adolescence to adulthood. It focuses on a specific group of immature neurons in the amygdala that mature during this period, which may influence behavioral changes associated with adolescence. By studying these neurons and their connections, the research aims to uncover how disruptions in amygdala development could relate to mental health disorders, particularly autism spectrum disorders. The approach includes both human studies and animal models to gain insights into the underlying neuronal circuitry.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and potential interventions for adolescents with autism spectrum disorders and related conditions.
How similar studies have gone: Previous studies have shown promising results in understanding brain development and its impact on behavior, suggesting that this research could build on established findings.
Where this research is happening
-
Children's Research Institute
Washington, United States Active
Researchers
- Principal investigator: Corbin, Joshua G — Children's Research Institute
- Study coordinator: Corbin, Joshua G
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.