Understanding how prior knowledge affects speech processing in people with schizophrenia who experience auditory hallucinations

Natural Speech Processing, the Influence of Prior Knowledge, and Auditory Hallucinations in Schizophrenia

NIH-funded research University of Rochester · NIH-10987198

This study is looking at how people with schizophrenia hear and understand speech, especially those who experience auditory hallucinations, to see how their past experiences affect what they hear compared to those who don’t have these hallucinations and healthy individuals.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-10987198 on NIH RePORTER

What this research studies

This research investigates the mechanisms behind auditory hallucinations (AH) in individuals with schizophrenia by examining how prior knowledge influences their processing of natural speech. Using advanced electroencephalography (EEG) technology, the study will analyze brain activity while participants listen to speech segments. The research aims to compare individuals with auditory hallucinations to those without, as well as to healthy controls, to identify differences in auditory processing and the impact of expectations on perception.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals diagnosed with schizophrenia, specifically those who experience auditory hallucinations as well as those who do not.

Not a fit: Patients who do not have a diagnosis of schizophrenia or who do not experience auditory hallucinations may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new, targeted interventions for individuals with schizophrenia who experience auditory hallucinations.

How similar studies have performed: Previous research has shown promising results in understanding auditory processing in schizophrenia, suggesting that this approach may yield valuable insights.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.