Understanding how prior knowledge affects speech processing in people with schizophrenia who experience auditory hallucinations
Official title: Natural Speech Processing, the Influence of Prior Knowledge, and Auditory Hallucinations in Schizophrenia
Funded at University of Rochester · NIH-10987198 · Data updated 2026-11-12
This study is looking at how people with schizophrenia hear and understand speech, especially those who experience auditory hallucinations, to see how their past experiences affect what they hear compared to those who don’t have these hallucinations and healthy individuals.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | July 1, 2024 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $423,500 |
| NIH project number | 1R21MH135314-01A1 |
| Project ID | NIH-10987198 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with schizophrenia, specifically those who experience auditory hallucinations as well as those who do not.
✕Less likely to help
Patients who do not have a diagnosis of schizophrenia or who do not experience auditory hallucinations may not benefit from this research.
What this research studies
This research investigates the mechanisms behind auditory hallucinations (AH) in individuals with schizophrenia by examining how prior knowledge influences their processing of natural speech. Using advanced electroencephalography (EEG) technology, the study will analyze brain activity while participants listen to speech segments. The research aims to compare individuals with auditory hallucinations to those without, as well as to healthy controls, to identify differences in auditory processing and the impact of expectations on perception.
Why it matters
Potential benefit: If successful, this research could lead to new, targeted interventions for individuals with schizophrenia who experience auditory hallucinations.
How similar studies have gone: Previous research has shown promising results in understanding auditory processing in schizophrenia, suggesting that this approach may yield valuable insights.
Where this research is happening
-
University of Rochester
Rochester, United States Active
Researchers
- Principal investigator: Thompson, Judy Lorraine — University of Rochester
- Study coordinator: Thompson, Judy Lorraine
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.