Understanding how glucose transport affects brain development and disorders
Official title: Determining the Role of Glucose Transporter 1 in Neural Development and Disease
Funded at Weill Medical Coll of Cornell Univ · NIH-11132125 · Data updated 2026-11-12
This study is looking at how a protein called GLUT1 helps the brain grow and develop, and how problems with this protein might be connected to conditions like Autism and Attention Deficit Disorder, using both mice and human samples to learn more about it.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 1, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $595,779 |
| NIH project number | 1R01NS138625-01A1 |
| Project ID | NIH-11132125 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with GLUT1-Deficiency Syndrome or those diagnosed with Autism or Attention Deficit Disorder.
✕Less likely to help
Patients without neurodevelopmental disorders or those not affected by glucose metabolism issues may not benefit from this research.
What this research studies
This research investigates the role of a specific glucose transporter, GLUT1, in the development of the brain and its potential link to neurodevelopmental disorders such as Autism and Attention Deficit Disorder. By studying both mouse and human models, the researchers aim to understand how glucose uptake influences the growth and differentiation of neural progenitor cells during brain development. The study will utilize advanced techniques to analyze how changes in GLUT1 expression can affect brain cell behavior and overall neurodevelopment.
Why it matters
Potential benefit: If successful, this research could lead to new insights and treatments for neurodevelopmental disorders linked to glucose metabolism.
How similar studies have gone: Previous research has shown promising results in understanding the role of glucose metabolism in brain development, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Pearson, Caroline Alayne — Weill Medical Coll of Cornell Univ
- Study coordinator: Pearson, Caroline Alayne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.