Understanding how gastrointestinal cancers start and progress
Translational Science of Gastrointestinal Cancer Initiation and Progression
This study is looking into how certain changes in the body can lead to gastrointestinal cancers like colorectal and esophageal cancer, with the goal of finding better ways to prevent and catch these cancers early, which could help patients get better treatment options.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Fred Hutchinson Cancer Center NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10913595 on NIH RePORTER |
What this research studies
This research investigates the initiation and progression of gastrointestinal cancers, particularly colorectal cancer and esophageal adenocarcinoma. It focuses on understanding the role of precancerous lesions and the surrounding tissue environment in cancer development. By studying molecular changes and tumor-promoting mechanisms, the research aims to identify new strategies for cancer prevention and early detection. Patients may benefit from insights that could lead to improved screening and treatment options for these cancers.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at high risk for colorectal cancer or esophageal adenocarcinoma, particularly those with precancerous lesions.
Not a fit: Patients with no history of gastrointestinal issues or those who do not have risk factors for these cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and early detection methods for gastrointestinal cancers, potentially saving lives.
How similar studies have performed: Previous research has shown promise in understanding the molecular mechanisms of cancer progression, indicating that this approach could yield valuable insights.
Where this research is happening
Seattle, United States
- Fred Hutchinson Cancer Center — Seattle, United States (Active)
Researchers
- Principal investigator: Yu, Ming — Fred Hutchinson Cancer Center
- Study coordinator: Yu, Ming
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.