Understanding how environment affects children's asthma and ADHD
Official title: ECHO II: Impact of environmental exposures on children's health and the co-morbidity of asthma and ADHD
Funded at Icahn School of Medicine at Mount Sinai · NIH-11311456 · Data updated 2026-11-12
This project looks at how environmental factors before birth might connect to asthma and ADHD in children, especially when both conditions happen together.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 21, 2016 |
| Project end | May 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $3,884,884 |
| NIH project number | 4UH3OD023290-10 |
| Project ID | NIH-11311456 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children, particularly those from communities like Northern Manhattan and the South Bronx, who have been followed from gestation through young adulthood, are the focus of this ongoing research.
✕Less likely to help
Patients who are not part of the existing ECHO cohort or similar long-term follow-up groups may not directly benefit from this specific data analysis.
What this research studies
Our center has a long history of looking into how a child's environment affects their health, from before they are born through young adulthood. We are particularly interested in communities like Northern Manhattan and the South Bronx, where many complex childhood diseases are common. This work helps us understand how things like air pollution and social factors might lead to conditions such as childhood asthma and Attention Deficit Hyperactivity Disorder (ADHD). By studying a large group of children, we hope to find common patterns of exposure that contribute to these conditions and why they often occur together.
Why it matters
Potential benefit: If successful, this work could lead to better ways to prevent and treat childhood asthma and ADHD by identifying risks earlier and improving referrals for related conditions.
How similar studies have gone: This project builds upon an established history of environmental health research in children and leverages a large existing cohort, suggesting a foundation of prior success in similar areas.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Miller, Rachel L — Icahn School of Medicine at Mount Sinai
- Study coordinator: Miller, Rachel L
Related research
Other NIH-funded projects on the same topics.
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Impact of environmental exposures on children's airway health and co-occurring ADHD
A large study following children to understand how prenatal and early-life exposures influence asthma and ADHD, and their overlap, with potential to guide prevention and early intervention.
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A study with children who have ADHD is testing how emotion regulation and thinking skills fit together to better understand why ADHD shows up differently in kids.
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This grant studies how group 2 innate lymphoid cells influence asthma in adults to help identify new ways to manage airway inflammation.
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Expanding understanding of asthma in kids through airways and blood profiling
A study at UC San Francisco will profile blood and nasal/sputum samples from 300 youth (including 200 with asthma) over a year to understand how environmental and social factors influence asthma in marginalized communities.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.