Impact of environmental exposures on children's airway health and co-occurring ADHD
Official title: ECHO II: Impact of environmental exposures on children's health and the co-morbidity of asthma and ADHD
Funded at Icahn School of Medicine at Mount Sinai · NIH-11375523 · Data updated 2026-11-12
A large study following children to understand how prenatal and early-life exposures influence asthma and ADHD, and their overlap, with potential to guide prevention and early intervention.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 21, 2016 |
| Project end | May 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $3,944,894 |
| NIH project number | 5UH3OD023290-11 |
| Project ID | NIH-11375523 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children from birth through early childhood, particularly in urban populations with higher exposure risks, whose health could be affected by environmental factors.
✕Less likely to help
Children without exposure-related risk factors or those not at risk for asthma or ADHD may see limited direct benefit.
What this research studies
This project follows children from gestation through early childhood to see how physical, chemical, and social factors in the environment affect airway health and neurodevelopment. Using data already collected by the ECHO program, researchers will look for patterns that link prenatal exposures to asthma and ADHD, and how these conditions may share common causes. The goal is to identify points where prevention and earlier referral for co-occurring issues could help kids and families. The study emphasizes translating findings into practical strategies for reducing risk and improving care in affected communities. Results could inform guidelines and public health actions to protect children’s health.
Why it matters
Potential benefit: If successful, the work could lead to earlier detection, better prevention strategies, and improved treatments for children with asthma and ADHD.
How similar studies have gone: Prior research has linked environmental exposures to asthma and neurodevelopmental outcomes, with growing evidence of comorbidity; this project builds on that foundation with a large, integrated cohort.
Where this research is happening
-
Icahn School of Medicine at Mount Sinai
New York, United States Active
Researchers
- Principal investigator: Miller, Rachel L — Icahn School of Medicine at Mount Sinai
- Study coordinator: Miller, Rachel L
Related research
Other NIH-funded projects on the same topics.
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-
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Understanding how a type of immune cell called ILC2s affect asthma in adults
This grant studies how group 2 innate lymphoid cells influence asthma in adults to help identify new ways to manage airway inflammation.
-
Expanding understanding of asthma in kids through airways and blood profiling
A study at UC San Francisco will profile blood and nasal/sputum samples from 300 youth (including 200 with asthma) over a year to understand how environmental and social factors influence asthma in marginalized communities.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.