Understanding how brain injuries affect aging and behavior
Official title: Targeting mechanisms of glycosaminoglycan accumulation and neurobehavioral dysfunction to improve outcomes from traumatic brain injury
Funded at Texas Tech University Health Scis Center · NIH-10641459 · Data updated 2026-11-12
This study is looking at how a traumatic brain injury might lead to problems in the brain as we get older, and it’s for anyone interested in understanding how injuries can affect brain health and behavior over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Texas Tech University Health Scis Center NIH-funded |
| Lab location | 1 site (Lubbock, United States) |
| Project start | April 15, 2025 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $192,737 |
| NIH project number | 1K22AG081264-01 |
| Project ID | NIH-10641459 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a traumatic brain injury and are at risk for developing age-related health issues.
✕Less likely to help
Patients who have not experienced a traumatic brain injury or those with pre-existing age-related diseases may not benefit from this research.
What this research studies
This research investigates the biological mechanisms that link traumatic brain injury (TBI) to age-related diseases. It focuses on how TBI may lead to the accumulation of specific molecules in the brain that disrupt normal function and contribute to behavioral changes. By studying a particular protein associated with TBI, the researchers aim to uncover new ways to prevent or reduce these negative outcomes. The approach includes using genetically modified mice to observe the effects of targeted mutations on brain health after injury.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve recovery and reduce the risk of age-related diseases in individuals who have suffered a traumatic brain injury.
How similar studies have gone: Other research has shown promising results in understanding the biological impacts of traumatic brain injury, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Texas Tech University Health Scis Center
Lubbock, United States Active
Researchers
- Principal investigator: Logsdon, Aric Flint — Texas Tech University Health Scis Center
- Study coordinator: Logsdon, Aric Flint
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.