Understanding how aortic dissections change over time
A Geometric and Morphoelastic Study of Aortic Dissection Evolution
This study is looking at how to better understand and predict the stability of type B aortic dissections using advanced imaging techniques, so that doctors can provide more personalized care and help patients know their risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project ID | NIH-10862611 on NIH RePORTER |
What this research studies
This research investigates the unpredictable nature of aortic dissections, particularly type B dissections, by analyzing their biomechanical stability through advanced imaging techniques. By utilizing modern geometric and computer vision methods, the study aims to identify specific patterns in imaging data that can help classify the risk associated with aortic fragility. The goal is to develop algorithms that can predict the stability of aortic dissections, allowing for personalized risk assessments and improved clinical management for patients. This approach seeks to uncover hidden geometric structures in CT angiography data that correlate with aortic dissection risk.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with type B aortic dissections who are undergoing imaging evaluations.
Not a fit: Patients with stable aortic conditions or those who do not have aortic dissections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better risk assessment and management strategies for patients with aortic dissections, potentially improving outcomes and reducing complications.
How similar studies have performed: While the approach is innovative, similar studies have shown promise in using imaging data to predict outcomes in other cardiovascular conditions.
Where this research is happening
Chicago, United States
- University of Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Pocivavsek, Luka — University of Chicago
- Study coordinator: Pocivavsek, Luka
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.