Understanding how aging affects language processing after a stroke

Brain Age in Aphasia

NIH-funded research University of South Carolina at Columbia · NIH-10945028

This study is looking at how getting older affects language difficulties after a stroke, and it aims to understand how changes in the brain can influence how severe these language issues are, so we can find better ways to help people with aphasia.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of South Carolina at Columbia NIH-funded
Lab location1 site (Columbia, United States)
Project IDNIH-10945028 on NIH RePORTER

What this research studies

This research investigates the relationship between aging and aphasia, a language processing disorder that often occurs after a stroke. By utilizing advanced neuroimaging techniques, the study aims to measure brain age and its impact on aphasia severity, particularly focusing on how age-related brain integrity influences communication abilities. The research seeks to identify personalized factors that contribute to the severity of aphasia, which could lead to improved treatment strategies for affected individuals. Participants may undergo brain imaging and cognitive assessments to help clarify these relationships.

Who could benefit from this research

Good fit: Ideal candidates for this research are stroke survivors experiencing chronic aphasia, particularly those who are older or have cardiovascular risk factors.

Not a fit: Patients who do not have aphasia or have not experienced a stroke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals suffering from aphasia after a stroke.

How similar studies have performed: Previous research has shown promising results in understanding the effects of brain aging on cognitive functions, suggesting that this approach could yield valuable insights.

Where this research is happening

Columbia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired brain injury
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.