TREAT-T2DM: AI-powered help to titrate diabetes treatments
Official title: Titration Response and Enhancement by AI Tools for T2DM (TREAT-T2DM)
Funded at Updoc Ai · NIH-11407615 · Data updated 2026-11-12
An AI tool called UpDoc Clinical Copilot helps manage diabetes medications remotely to improve blood sugar control for people with type 2 diabetes, especially in underserved communities.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Updoc Ai NIH-funded |
| Lab location | 1 site (Los Altos, United States) |
| Project start | September 1, 2026 |
| Project end | February 29, 2028 |
| Funding year | 2026 |
| Award (this year) | $1,467,300 |
| NIH project number | 1R44DK145399-01A1 |
| Project ID | NIH-11407615 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with type 2 diabetes enrolled in primary care clinics, especially from underserved populations, who are candidates for remote management.
✕Less likely to help
Patients already on optimal therapy with no room for titration or those unable to use remote monitoring tech may see little benefit.
What this research studies
This project tests an AI assistant that can guide and adjust diabetes prescriptions to help patients reach safer blood sugar levels. It will compare the AI-assisted approach to standard remote monitoring in a randomized trial with up to 200 participants from Stanford-affiliated clinics. The study looks at glycemic control, healthcare costs, and how both patients and providers feel about using the AI platform. The goal is to determine if this technology can make diabetes care more effective, affordable, and accessible.
Why it matters
Potential benefit: If successful, patients could see better blood sugar control and more convenient diabetes care with fewer clinic visits.
How similar studies have gone: Prior digital health tools have improved self-management, but this AI-titration approach is an innovation that combines prescribing actions with remote monitoring.
Where this research is happening
-
Updoc Ai
Los Altos, United States Active
Researchers
- Principal investigator: Vakili, Sharif — Updoc Ai
- Study coordinator: Vakili, Sharif
Related research
Other NIH-funded projects on the same topics.
-
Peer support to help older adults with type 2 diabetes in rural Appalachia
Seeing if trained peer support can help older adults in rural Appalachian communities better manage their type 2 diabetes.
-
Continuous Glucose Monitoring versus Traditional Self-Monitoring for Non-Insulin Treated Adults with Type 2 Diabetes
This grant tests whether wearing a CGM helps adults with type 2 diabetes who aren’t using insulin manage blood sugar better than traditional finger-stick checks.
-
Conditional cash transfers and basic needs support for adults with type 2 diabetes
A funding-backed program will test whether helping low-income adults with type 2 diabetes meet basic needs improves their diabetes control and overall health.
-
Predicting heart and blood vessel disease risk in type 2 diabetes using immune-cell computer tools
This project uses new computer tools to read immune cell behavior and predict heart and blood vessel disease risk in people with type 2 diabetes.
-
Using cash incentives to improve health for African Americans with diabetes
This study is looking at how giving cash rewards for healthy activities can help African Americans with type 2 diabetes living in city neighborhoods improve their health and manage stress from poverty and racism.
-
Helping older adults with type 2 diabetes in Appalachia through peer support.
This study is all about helping older adults with type 2 diabetes in rural Appalachia by creating a friendly support program where they can share experiences and learn from each other to take better care of their health.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.