NIH-funded research R01 grant

Continuous Glucose Monitoring versus Traditional Self-Monitoring for Non-Insulin Treated Adults with Type 2 Diabetes

Official title: Efficacy of Continuous Glucose Monitoring Relative to Traditional Self-Monitoring of Blood Glucose in Non-Insulin Treated Adults with Poorly Controlled T2DM

Funded at State University of New York at Buffalo · NIH-11448826 · Data updated 2026-11-12

This grant tests whether wearing a CGM helps adults with type 2 diabetes who aren’t using insulin manage blood sugar better than traditional finger-stick checks.

More T2DM research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo
NIH-funded
Lab location1 site (Amherst, United States)
Project startJuly 1, 2026
Project endJune 30, 2031
Funding year2026
Award (this year)$799,752
NIH project number1R01DK149293-01
Project IDNIH-11448826 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 21 and older with type 2 diabetes who are not treated with insulin and who currently monitor blood glucose.

Less likely to help

Patients who are not willing or able to use CGMs or who have contraindications to CGM use may not benefit.

What this research studies

If approved, researchers will compare CGM to standard finger-stick monitoring in adults with type 2 diabetes who are not on insulin. The study will look at health outcomes like HbA1c, blood pressure, and lipids, as well as lifestyle factors such as diet and exercise adherence. It will also examine whether CGMs are cost-effective in this population and if providing CGMs plus basic support improves quality of life. The work will use real-world data to understand how patients actually use CGMs outside of specialized clinics. Results could inform payer coverage and everyday treatment choices for many adults with type 2 diabetes.

Why it matters

Potential benefit: If successful, patients may experience better blood sugar control and quality of life, with potential cost savings for healthcare.

How similar studies have gone: Previous studies show CGMs can improve glucose control in some populations, but data in non-insulin treated type 2 diabetes are limited.

Where this research is happening

  • State University of New York at Buffalo
    Amherst, United States
    Active

Researchers

  • Principal investigator: Egede, Leonard E. — State University of New York at Buffalo
  • Study coordinator: Egede, Leonard E.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.