NIH-funded research NIH-funded research

Tissue imaging and spatial profiling resources for tumor studies

Official title: Core 2: Tissue Imaging and Profiling Core

Funded at Institute for Systems Biology · NIH-11415811 · Data updated 2026-11-12

A core research resource helps researchers study tumor tissues with advanced imaging and multi-omic profiling to understand their biology.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionInstitute for Systems Biology
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 22, 2022
Project endAugust 31, 2027
Funding year2026
Award (this year)$416,279
NIH project number5U54CA274509-05
Project IDNIH-11415811 on NIH RePORTER

Who could benefit from this research

Could help

Patients with tumor tissues available for imaging and profiling studies, either via clinical archives or research collaborations.

Less likely to help

Patients without access to preserved tumor samples or who are not involved in projects using these cores may not directly benefit.

What this research studies

This grant provides access to high-end tissue imaging and profiling platforms that work with FFPE and lightly preserved tissues. It supports analyzing regions of interest with transcriptome and proteome data at high multiplexing levels. The core also includes image analysis and informatics software to translate tissue data into meaningful biology for cancer patients. Researchers from multiple projects can use these tools to map cellular landscapes within tumors.

Why it matters

Potential benefit: If successful, patients may benefit from faster translation of tumor biology insights into targeted therapies.

How similar studies have gone: Similar spatial profiling approaches have yielded rich tumor maps and actionable insights in prior work.

Where this research is happening

  • Institute for Systems Biology
    Seattle, United States
    Active

Researchers

  • Principal investigator: Fan, Rong — Institute for Systems Biology
  • Study coordinator: Fan, Rong

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.