Testing antiplatelet approaches in psoriasis to improve blood vessel health
Official title: Testing various antiplatelet strategies in psoriasis to improve vascular health
Funded at New York University School of Medicine · NIH-11433065 · Data updated 2026-11-12
A study at NYU School of Medicine will test antiplatelet strategies to reduce heart and blood vessel risk in adults with psoriasis.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | September 4, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $845,590 |
| NIH project number | 1R01HL188015-01 |
| Project ID | NIH-11433065 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with psoriasis who may be at elevated cardiovascular risk, under clinician supervision.
✕Less likely to help
Participants without cardiovascular risk factors or those unable to tolerate antiplatelet therapy may see little direct benefit.
What this research studies
This project looks at how platelets contribute to cardiovascular risk in people with psoriasis and tests antiplatelet therapies to see if they can lower early blood vessel problems. The research builds on findings that psoriasis platelets are more active and can drive inflammation in blood vessels. By studying platelet behavior and responses in adults with psoriasis, the team hopes to identify safer ways to prevent heart disease in this population. Participation would involve clinically assessing responses to antiplatelet approaches and monitoring for safety and bleeding risks.
Why it matters
Potential benefit: If successful, the study could lead to new strategies to prevent cardiovascular disease in people with psoriasis.
How similar studies have gone: Prior trials focused on skin symptoms and did not convincingly reduce cardiovascular risk, making this approach exploratory but promising.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Garshick, Michael Seth — New York University School of Medicine
- Study coordinator: Garshick, Michael Seth
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.