NIH-funded research NIH-funded research

Team-based care for pregnant women with opioid use disorder in rural clinics

Official title: Impact of healthcare delivery models for pregnant women with opioid use disorder

Funded at University of Pittsburgh at Pittsburgh · NIH-11454658 · Data updated 2026-11-12

A team-based care model is being adapted for rural obstetric settings to help pregnant women with opioid use disorder start and continue medications and improve health outcomes for them and their babies.

More Opioid Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startSeptember 30, 2024
Project endJune 30, 2030
Funding year2026
Award (this year)$1,053,970
NIH project number4R33DA061377-02
Project IDNIH-11454658 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant women with opioid use disorder receiving care at participating rural obstetric sites in Northwest Pennsylvania.

Less likely to help

Pregnant women without OUD or those not engaged with any MOUD approach may see no direct benefit.

What this research studies

This project tests a rural-adapted, team-based healthcare delivery approach for pregnant women with opioid use disorder. It will be conducted across three obstetric sites in Northwest Pennsylvania to see if the model increases initiation and ongoing use of medications for OUD and improves related health outcomes. The study uses a non-randomized, Type 1 hybrid design to examine both implementation and effects in real-world settings. By focusing on non-tertiary and rural clinics, the research aims to broaden access to MOUD and address co-occurring mental health needs. Results will guide how rural obstetric services can integrate comprehensive care for mothers and their children.

Why it matters

Potential benefit: If successful, the model could improve MOUD uptake and maternal-child health outcomes in rural settings.

How similar studies have gone: Prior studies suggest team-based approaches can improve care coordination, but adaptation to rural obstetric settings remains to be proven.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Krans, Elizabeth E — University of Pittsburgh at Pittsburgh
  • Study coordinator: Krans, Elizabeth E

Related research

Other NIH-funded projects on the same topics.

  • Tailored services and childcare for pregnant women in opioid use disorder treatment

    A national study looks at how pregnancy-focused addiction treatment programs can improve access to medications, childcare, and support for pregnant or new mothers with opioid use disorder.

    NIH research Univ of Arkansas for Med Scis · Little Rock, United States · NIH-11392700

  • Parenting support for pregnant people with opioid use disorder

    This project adapts a proven parenting program to help pregnant people with opioid use disorder build parenting skills and support from pregnancy into early parenthood.

    NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11311340

  • Improving parenting for pregnant women with opioid use disorder

    This study is looking to help pregnant women who are dealing with opioid use disorder by providing support and resources to improve their parenting skills and overall well-being during pregnancy, so they can have a healthier start for themselves and their babies.

    NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11047681

  • Comparing withdrawal and medication treatments for pregnant women with opioid use disorder

    This study is looking at two different ways to help pregnant women who are dealing with opioid use disorder—either going through a supervised withdrawal or using ongoing medication—and it aims to find out which method is safer and more effective for both moms and their babies.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-10375543

  • Systems analysis to improve opioid use disorder care after jail release (SAIA-MOUD)

    A program to help people with opioid use disorder get better, faster, and safer care after they leave jail.

    NIH research University of Washington · Seattle, United States · NIH-11599161

  • Precise epigenetic drugs for opioid addiction

    A tiny, targeted drug approach is being developed to help people with opioid use disorder by rewriting the epigenetic signals in the brain to reduce cravings and relapse risk.

    NIH research Boston Interactome, INC. · Boston, United States · NIH-11578588

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.