Supportive Care for Lung Cancer Patients with Targeted Therapy
Official title: Optimizing Supportive Care for Patients with Metastatic Lung Cancer in the Era of Precision Oncology
Funded at Massachusetts General Hospital · NIH-11395321 · Data updated 2026-11-12
A patient-facing program tests a palliative care approach tailored for people living with oncogene-driven metastatic lung cancer to help with uncertainty, self-care, and discussions about goals and values.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | June 1, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $271,934 |
| NIH project number | 5K08CA263549-05 |
| Project ID | NIH-11395321 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with metastatic lung cancer driven by targetable genetic alterations who are navigating ongoing treatment and living with life-limiting disease.
✕Less likely to help
Patients without oncogene-driven lung cancer or those not managing uncertainty about prognosis may not directly benefit.
What this research studies
This grant funds a five-year plan to create and pilot a palliative and survivorship-informed care program specifically for people whose lung cancer has targetable genetic changes. The program aims to adapt strategies from survivorship care to address ongoing symptoms, uncertainty, and decision-making about treatment and life planning. Researchers will refine the intervention with feedback from patients and caregivers, and test its feasibility and acceptability in a randomized trial against usual care. The study will look at distress from prognosis, confidence in managing chronic disease, awareness of prognosis, and conversations about goals and values to guide future care decisions.
Why it matters
Potential benefit: If successful, patients could experience less distress and feel more confident in managing their illness and conversations about care preferences.
How similar studies have gone: Previous studies in palliative care and survivorship-informed interventions have shown promise in improving quality of life and decision-making.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Petrillo, Laura Anne — Massachusetts General Hospital
- Study coordinator: Petrillo, Laura Anne
Related research
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Improving care for patients with advanced lung cancer using personalized approaches
This study is looking to improve support for people with metastatic lung cancer who have certain genetic mutations by testing a new way to help them feel more comfortable and make better decisions about their care, based on what they and their doctors think is important.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.