NIH-funded research NIH-funded research

Supported Employment to Help Youth with Early Psychosis in Uganda

Official title: Recovery and Inclusion through Supported Employment for People Experiencing Psychosis in Low Resource Settings (RISE)

Funded at New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-11519495 · Data updated 2026-11-12

A patient-facing plan to help young people in Uganda with early psychosis find and keep jobs through an adapted IPS program.

More Psychosis research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
NIH-funded
Lab location1 site (New York, United States)
Project startMay 1, 2026
Project endApril 30, 2029
Funding year2026
Award (this year)$64,850
NIH project number3R34MH141628-01S1
Project IDNIH-11519495 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are 12-20 year olds in Uganda with early psychosis who are at or near the start of work or education goals and who would benefit from supported employment.

Less likely to help

Patients without access to or interest in employment support services or those not in early psychosis care may see little or no benefit.

What this research studies

This project aims to adapt and pilot an evidence-based employment support, IPS, for young Ugandan adults experiencing early psychosis. It emphasizes community engagement to fit local culture, economy, and services, and plans to test whether IPS can improve real-world employment outcomes. The study focuses on adolescents and young adults in Uganda who are navigating psychosis and education or work goals, with a strong emphasis on reducing caregiver burden. Researchers will work with communities to identify barriers and facilitators, gather insights from interviews, and implement the adapted IPS in early psychosis services in Kampala. The goal is to create a practical, scalable pathway from treatment to meaningful work and independence.

Why it matters

Potential benefit: If successful, it could help young people with psychosis gain and maintain employment, improving independence and reducing caregiver strain.

How similar studies have gone: IPS has improved employment outcomes in high-income settings, but this is the first systematic attempt to adapt and test it in a low-resource African context.

Where this research is happening

  • New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
    New York, United States
    Active

Researchers

  • Principal investigator: Florence, Ana Carolina — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
  • Study coordinator: Florence, Ana Carolina

Related research

Other NIH-funded projects on the same topics.

  • Psychosis in diverse settings across the world

    This project studies how psychotic disorders show up and respond to treatment in adults with diverse backgrounds, including populations in Africa, the Caribbean, and other Global South settings.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-11592428

  • Psychosis in Diverse Settings: Understanding Symptoms and Treatment Across Global South

    A human-facing study will look at how psychotic disorders present and respond to treatment in adults from Africa, the Caribbean, and other Global South settings, using genetic and clinical data.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-11592427

  • A new online brain-scan-style tool to spot early psychosis risk

    A new online-based set of tasks and a computer model aims to identify people at high risk for developing psychosis earlier and more accurately.

    NIH research Northwestern University · Chicago, United States · NIH-11590585

  • Genetic clues for early-onset psychosis in Latino youth

    This project looks at the genes of young people with early-onset psychosis and compares them with similar youths without psychosis to find genetic factors that contribute to the illness.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11554752

  • Biomarkers to tailor rehab for Veterans with schizophrenia

    A clinician-scientist is developing a brain-based biomarker to guide personalized rehabilitation for Veterans with schizophrenia.

    NIH research VA San Diego Healthcare System · San Diego, United States · NIH-11552825

  • Computational analysis of facial expression in early psychosis

    Aims to develop computer-based measures of facial expression in people at risk for or with schizophrenia to help track symptoms and guide future trials.

    NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11539126

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.