NIH-funded research NIH-funded research

STOP Unhealthy Substance Use Now: Faster, Better Primary Care for SUDs

Official title: The STop UNhealthy Substance Use Now Trial (STUN II)

Funded at Ohio State University · NIH-11421122 · Data updated 2026-11-12

A practical plan to help primary care clinics screen for and manage substance use disorders more effectively using different support methods.

More Substance Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 30, 2023
Project endJuly 31, 2027
Funding year2026
Award (this year)$615,707
NIH project number5R18HS029782-04
Project IDNIH-11421122 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 21 and older who are patients in participating primary care clinics and have or are at risk for substance use disorders.

Less likely to help

Patients in clinics that do not adopt the intervention or that do not engage with the implementation strategies may see no change in care.

What this research studies

This project partners with primary care practices to rapidly implement proven approaches for identifying and treating unhealthy alcohol and other substance use. It compares facilitation support alone to combinations that include learning collaboratives and performance incentives, all aimed at improving screening and evidence-based care. The study will enroll 48 clinics and track how well each implementation strategy works in real-world settings. If successful, it could help more patients get timely help for substance use in a usual care environment.

Why it matters

Potential benefit: Patients could receive earlier identification and better management of substance use in their regular doctor visits.

How similar studies have gone: Prior implementation studies show that facilitation and collaborative approaches can improve uptake of screening and treatment guidelines in primary care.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Jonas, Daniel E — Ohio State University
  • Study coordinator: Jonas, Daniel E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.