Standardizing Behavioral and Social Research in Alzheimer’s through Ontology-Based Approaches
Official title: Standardizing and Harmonizing Behavioral and Social Science Research Factors in Alzheimer's Disease through Ontology-Based Approaches
Funded at Mayo Clinic Jacksonville · NIH-11399275 · Data updated 2026-11-12
A Mayo Clinic team is building an organized way to study how daily behaviors and social factors affect Alzheimer’s and related dementias to improve care and caregiver support.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $760,722 |
| NIH project number | 5U01AG088076-03 |
| Project ID | NIH-11399275 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with Alzheimer’s disease or related dementias, and their caregivers, who may benefit from improved behavioral and social interventions.
✕Less likely to help
Patients looking for immediate drug therapies or those not engaged with behavioral and social aspects of care may see less direct benefit.
What this research studies
This project focuses on non-drug approaches, like exercise programs, mental stimulation, diet, and social activities, to understand how they influence ADRD risk and quality of life. Researchers will develop and apply ontology-based representations to harmonize behavioral and social data from diverse sources, making it easier to combine findings. By creating standardized language and data links, the project aims to reveal how environment, culture, and care practices shape outcomes for people living with ADRD and their families. The work will inform better-tailored interventions, caregiver resources, and policies that support affected communities.
Why it matters
Potential benefit: If successful, patients with ADRD could receive more personalized non-pharmacologic care strategies and better support systems.
How similar studies have gone: Previous work shows that behavioral and social factors impact ADRD outcomes, and harmonization efforts can enhance data integration for better insights.
Where this research is happening
-
Mayo Clinic Jacksonville
Jacksonville, United States Active
Researchers
- Principal investigator: Tao, Cui — Mayo Clinic Jacksonville
- Study coordinator: Tao, Cui
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.