NIH-funded research NIH-funded research

Spinal Direct Current Stimulation to Improve Breathing After Cervical Cord Injury

Official title: Spinal Direct Current Stimulation to Enhance Breathing Following Cervical Spinal Cord Injury

Funded at Ohio State University · NIH-11416964 · Data updated 2026-11-12

A non-invasive therapy using gentle electrical stimulation to help people with spinal cord injuries breathe better.

More Cervical Spinal Cord Injury research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startApril 10, 2024
Project endMarch 31, 2029
Funding year2026
Award (this year)$249,000
NIH project number4R00NS133388-03
Project IDNIH-11416964 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates would be individuals with cervical spinal cord injury who have respiratory impairment and could benefit from neuromodulatory therapies.

Less likely to help

Patients without respiratory dysfunction related to SCI or those unable to participate in non-invasive neuromodulation would be less likely to benefit.

What this research studies

This project tests a non-invasive, low-intensity electrical technique (tsDCS) to boost respiratory function in a rodent model of cervical spinal cord injury. The study builds on Dr. Rana’s experience in SCI neurobiology and respiratory control to explore how neuromodulation can enhance breathing after injury. The University of Florida environment and its Breathing Research and Therapeutics Center will support the work with experts in respiratory motor control and SCI rehabilitation.

Why it matters

Potential benefit: If successful, this approach could lead to new ways to improve breathing and reduce respiratory complications in people with SCI.

How similar studies have gone: Previous work in neuromodulation and respiratory control has shown potential for improving breathing, but translating to clinical benefit requires further study.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: Rana, Sabhya — Ohio State University
  • Study coordinator: Rana, Sabhya

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.