Spinal cord stimulation to manage blood pressure after spinal cord injury
Official title: Acute and Chronic Repercussions of Spinal Cord Stimulation following Spinal Cord Injury
Funded at Mayo Clinic Rochester · NIH-11366139 · Data updated 2026-11-12
A Mayo Clinic study will test how spinal cord stimulation affects blood pressure stability in people with spinal cord injury.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | July 21, 2026 |
| Project end | May 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $622,784 |
| NIH project number | 1R01NS142427-01A1 |
| Project ID | NIH-11366139 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with spinal cord injury who experience blood pressure instability or autonomic dysfunction may be eligible.
✕Less likely to help
Individuals without spinal cord injury or without blood pressure instability are unlikely to benefit.
What this research studies
If you have a spinal cord injury, unstable blood pressure can be dangerous. This project will examine how short-term and longer-term spinal cord stimulation influences blood pressure and autonomic control. Researchers will use laboratory autonomic tests and pilot stimulation approaches to see how activation of the sympathetic system changes blood pressure, while watching for possible downsides like autonomic dysreflexia. The goal is to understand when stimulation helps and when it could cause problems, guiding safer future treatments.
Why it matters
Potential benefit: If successful, this work could lead to safer strategies to stabilize blood pressure for people with spinal cord injuries.
How similar studies have gone: Prior case studies suggest stimulation can raise blood pressure, but this project will clarify mechanisms and safety.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Solinsky, Ryan — Mayo Clinic Rochester
- Study coordinator: Solinsky, Ryan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.