Smartwatch-based monitoring to improve hormone replacement therapy for menopause
Official title: SMART-HRT: Smartwatch-Based Monitoring and Real-Time Tracking for Optimizing Hormone Replacement Therapy Efficacy in Menopause.
Funded at Amissa, INC. · NIH-11316421 · Data updated 2026-11-12
A smartwatch-based program tests whether real-time tracking can help optimize hormone replacement therapy for menopausal symptoms and potentially reduce cognitive risks.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Amissa, INC. NIH-funded |
| Lab location | 1 site (Charlotte, UNITED STATES) |
| Project start | September 17, 2026 |
| Project end | September 16, 2027 |
| Funding year | 2026 |
| Award (this year) | $313,211 |
| NIH project number | 1R43AG099614-01 |
| Project ID | NIH-11316421 on NIH RePORTER |
Who could benefit from this research
✓Could help
Women aged roughly 45-65 undergoing menopausal changes who are considering or receiving hormone replacement therapy.
✕Less likely to help
Women not using hormone therapy or those with contraindications to such treatment.
What this research studies
This grant studies how wearable sensors and AI-powered analysis can monitor menopausal symptoms in real time to guide hormone therapy. It builds on prior smartwatch work to capture vasomotor symptoms, sleep quality, and related factors outside a clinic. The goal is to understand how real-time data can tailor treatment to improve sleep, mood, and daily functioning, while minimizing side effects. If successful, this approach could make symptom management more convenient and accessible for many women, including those with limited access to specialized care.
Why it matters
Potential benefit: If successful, patients could experience more personalized symptom relief and better quality of life with fewer side effects.
How similar studies have gone: Previous studies show wearables can track menopausal symptoms and sleep patterns; this project extends that work to guide therapy decisions.
Where this research is happening
-
Amissa, INC.
Charlotte, United States Active
Researchers
- Principal investigator: Corkey, Jon Andrew — Amissa, INC.
- Study coordinator: Corkey, Jon Andrew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.