Sleep data that predict opioid treatment outcomes
Official title: Value of Sleep Metrics in Predicting Opioid-Use Disorder Treatment Outcomes: Leadership and Data Coordinating Center
Funded at Harvard Pilgrim Health Care, INC. · NIH-11398231 · Data updated 2026-11-12
A big multi-site study will look at sleep and circadian patterns to help predict how well people with opioid-use disorder do when on standard treatments.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Pilgrim Health Care, INC. NIH-funded |
| Lab location | 1 site (Canton, UNITED STATES) |
| Project start | September 30, 2023 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $678,723 |
| NIH project number | 5U01DA059472-04 |
| Project ID | NIH-11398231 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with opioid-use disorder enrolled in MOUD programs who consent to sleep monitoring and data sharing.
✕Less likely to help
Patients without sleep disturbances or those not participating in long-term MOUD follow-up may see limited benefit.
What this research studies
This project will bring together experts in sleep science and addiction medicine to collect and analyze sleep metrics from people receiving MOUD across multiple sites. It will use data coordination and centralized leadership to identify which sleep patterns are linked to staying in treatment and better outcomes. The goal is to uncover sleep-related markers that could guide personalized care in OUD treatment.
Why it matters
Potential benefit: If successful, patients may receive more tailored treatment plans that consider sleep health, potentially improving retention and outcomes in MOUD.
How similar studies have gone: Previous research shows sleep problems predict treatment dropout, but this study aims to clarify which sleep measures are most predictive in early recovery.
Where this research is happening
-
Harvard Pilgrim Health Care, INC.
Canton, United States Active
Researchers
- Principal investigator: Wang, Rui — Harvard Pilgrim Health Care, INC.
- Study coordinator: Wang, Rui
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.