Secure platform to study HIV prognosis and treatment effectiveness across the U.S., Canada, and Europe
Official title: A secure analytics platform to study the prognosis of people with HIV in the USA, Canada and Europe and comparative effectiveness of treatment regimens: the Antiretroviral Therapy Cohort Collaboration
Funded at University of Bristol · NIH-11414986 · Data updated 2026-11-12
A secure data platform will help researchers learn how people living with HIV fare over time and which ART regimens work best, across North America and Europe.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Bristol NIH-funded |
| Lab location | 1 site (Bristol, United Kingdom) |
| Project start | August 7, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $470,636 |
| NIH project number | 5R01AI181733-03 |
| Project ID | NIH-11414986 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV who are on antiretroviral therapy across North America and Europe.
✕Less likely to help
Patients not receiving ART or not contributing data to the ART-CC cohorts may see no direct benefit.
What this research studies
This project creates a protected data environment for HIV cohorts to analyze prognosis and treatment outcomes in people on antiretroviral therapy. Researchers will use standardized, privacy-preserving data and reproducible code to compare modern ART regimens. The approach prioritizes participant privacy and controlled data export, aiming to enable broader collaboration while protecting patient information. The work builds on the ART-CC collaboration, expanding access for external researchers in a secure, governed framework.
Why it matters
Potential benefit: If successful, patients could benefit from clearer guidance on prognosis and which ART strategies optimize health and longevity.
How similar studies have gone: Previous HIV cohort collaborations have improved understanding of causes of death and treatment outcomes; this platform aims to extend that success with enhanced privacy protections.
Where this research is happening
-
University of Bristol
Bristol, United Kingdom Active
Researchers
- Principal investigator: Sterne, Jonathan — University of Bristol
- Study coordinator: Sterne, Jonathan
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.