A center focused on immunotherapy for pediatric cancers.
Pediatric Ohio-New York Cancer (Peds-ONC) Immunotherapy Center
This study is exploring new ways to use the body's immune system to fight childhood cancers, aiming to create better treatments for kids whose cancers haven't responded well to standard therapies.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project ID | NIH-9839924 on NIH RePORTER |
What this research studies
The Pediatric Ohio-New York Cancer (Peds-ONC) Immunotherapy Center aims to develop innovative immunotherapy approaches to treat pediatric cancers by harnessing both innate and adaptive immune responses. This research focuses on overcoming barriers to using natural killer (NK) cells and CAR-NK cells as effective cancer treatments, breaking tolerance to cancer-associated proteins, and enhancing immunotherapies by targeting suppressive immune cells. Patients may benefit from cutting-edge therapies that could improve outcomes for pediatric cancers resistant to conventional treatments.
Who could benefit from this research
Good fit: Ideal candidates for participation are children diagnosed with various types of pediatric cancers.
Not a fit: Patients with non-cancerous conditions or those who do not have pediatric cancers may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective immunotherapy options for children with cancer.
How similar studies have performed: Previous research has shown promise in utilizing immunotherapy approaches for pediatric cancers, indicating potential for success in this novel initiative.
Where this research is happening
Columbus, United States
- Research Inst Nationwide Children's Hosp — Columbus, United States (Active)
Researchers
- Principal investigator: Cripe, Timothy P — Research Inst Nationwide Children's Hosp
- Study coordinator: Cripe, Timothy P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.