Testing a skin patch to treat peanut allergies
Official title: Safety and Tolerability of TASIS-Peanut (Targeted Allergen Specific Immunotherapy within the Skin) patch for the Treatment of Peanut Allergy
Funded at Moonlight Therapeutics, INC. · NIH-11305456 · Data updated 2026-11-12
This study is testing a new skin patch that delivers peanut allergens to help people with peanut allergies feel less sensitive to them, and it's open to both kids and adults who want to improve their lives and lower their risk of serious allergic reactions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Moonlight Therapeutics, INC. NIH-funded |
| Lab location | 1 site (Marietta, UNITED STATES) |
| Project start | June 2, 2025 |
| Project end | May 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $999,658 |
| NIH project number | 4U44AI165328-02 |
| Project ID | NIH-11305456 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals of all ages who have a diagnosed peanut allergy.
✕Less likely to help
Patients who are not allergic to peanuts or those with severe skin conditions may not benefit from this research.
What this research studies
This research investigates a new treatment for peanut allergies using a skin patch that delivers targeted allergen immunotherapy. The patch, known as TASIS-Peanut, uses microneedles to administer allergens into the top layers of the skin, aiming to desensitize patients to peanuts. By participating, patients may help evaluate the safety and tolerability of this innovative approach, which could significantly improve their quality of life and reduce the risk of severe allergic reactions. The study focuses on both children and adults who suffer from peanut allergies.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option that reduces the risk of life-threatening allergic reactions to peanuts.
How similar studies have gone: While there are existing treatments for food allergies, this specific approach using targeted allergen immunotherapy via a skin patch is novel and has not been extensively tested in prior research.
Where this research is happening
-
Moonlight Therapeutics, INC.
Marietta, United States Active
Researchers
- Principal investigator: Patel, Samirkumar — Moonlight Therapeutics, INC.
- Study coordinator: Patel, Samirkumar
Related research
Other NIH-funded projects on the same topics.
-
Safety and tolerability of a skin patch to treat peanut allergy
A new skin patch designed to desensitize peanut allergy is being studied to see if it is safe and tolerable for people with peanut allergy.
-
Boosting immune response to fight cancer
This study is exploring a new way to help your immune system better fight cancer by tweaking certain cells in your body, and it aims to improve treatment for people with advanced cancer.
-
A center focused on immunotherapy for pediatric cancers.
This study is exploring new ways to use the body's immune system to fight childhood cancers, aiming to create better treatments for kids whose cancers haven't responded well to standard therapies.
-
Algorithms to find HLA-E neoantigens for cancer immunotherapy
Aims to develop computer methods to discover tumor-specific targets presented by HLA-E to guide new T cell therapies for cancer.
-
Immunotherapy for glioblastoma: advancing treatment and understanding
A patient-friendly summary of a grant exploring new immune-based treatments for glioblastoma to improve options for people affected by this brain cancer.
-
New Horizons in preventing and treating food allergy
A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.