Safe, digitally-enabled cancer pain care for patients and survivors
Official title: Achieving Safe, Comprehensive, Digitally-Enabled Cancer Pain managemeNT” (ASCENT) Clinical Trial
Funded at Mayo Clinic Rochester · NIH-11400451 · Data updated 2026-11-12
A nationwide Mayo Clinic-led program tests a digitally-supported, team-based approach to managing cancer pain that may help patients and survivors receive better, safer pain care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project start | September 6, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,594,502 |
| NIH project number | 5R33CA278594-05 |
| Project ID | NIH-11400451 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults (21+) with advanced cancer, cancer pain, or as cancer survivors who have ongoing pain management needs.
✕Less likely to help
Patients without persistent cancer pain or those unable to access digital health tools may see limited or no direct benefit.
What this research studies
This project aims to improve cancer pain management by combining multi-modal care with collaborative, team-based processes and electronic health record tools. It targets adults with advanced cancer or survivors who experience painful symptoms and barriers to effective treatment. The study builds on a history of CCM and MMPC work, adapting it to diverse and resource-limited settings to ensure broader access. Participation would involve routine care augmented by digital tools that help care teams monitor pain and coordinate treatment.
Why it matters
Potential benefit: If successful, patients could experience better pain control with safer, more personalized care and fewer unnecessary opioid-related risks.
How similar studies have gone: Previous CCM and MMPC approaches have shown promise, and integrating EHRs with team-based care is an area with emerging positive results.
Where this research is happening
-
Mayo Clinic Rochester
Rochester, United States Active
Researchers
- Principal investigator: Cheville, Andrea Lynne — Mayo Clinic Rochester
- Study coordinator: Cheville, Andrea Lynne
Related research
Other NIH-funded projects on the same topics.
-
Cancer Pain Management for Asian American Breast Cancer Survivors with Depressive Symptoms
A technology-based program helps Asian American breast cancer survivors with depressive symptoms manage chronic pain more effectively from home using a web app and mobile tools.
-
How State Cannabis Laws Affect Cancer Pain Care and Patient Well-being
This project looks at how state laws about cannabis might change how people with cancer manage their pain and how they feel overall.
-
Safe, comprehensive digital cancer pain care (ASCENT)
A digital care program aims to help adults with advanced cancer get safer, more complete pain treatment.
-
Tech-based pain support for Asian American breast cancer survivors
This project is building an easy-to-use web and mobile program to help Asian American breast cancer survivors with chronic pain and depression get personalized information and coaching.
-
Impact of Cannabis Laws on Cancer Pain in Patients
A mixed-methods study exploring how state cannabis laws affect cancer pain management and outcomes for adults with cancer.
-
Training healthcare providers to use hypnosis for managing cancer pain
This study is teaching cancer care providers how to use hypnosis to help reduce pain for cancer patients, making their treatment experience more comfortable and improving their overall quality of life.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.