Role of CPT1 activation in spinal cord injury

Who could benefit from this research

What this research studies

Traumatic spinal cord injury causes serious, lasting problems and there aren’t good treatments yet. The project focuses on how lipid metabolism and fatty acid breakdown affect damage and signaling in the injured nervous system. By studying CPT1’s role in mitochondrial fatty acid oxidation, researchers hope to identify pathways that could be targeted to improve function after SCI. The work combines molecular and cellular approaches to understand how metabolic changes influence nerve cell survival and repair. If successful, it could point to new strategies to protect neurons and support recovery.

Why it matters

Where this research is happening

• Indiana University Indianapolis
  Indianapolis, United States Active

Researchers

• Principal investigator: Liu, Nai-Kui — Indiana University Indianapolis
• Study coordinator: Liu, Nai-Kui

Related research

Other NIH-funded projects on the same topics.

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• Predicting and Preventing Chronic Aspiration After Traumatic Cervical Spinal Cord Injury

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.