NIH-funded research Sbir 2 grant

Retraining brain pathways to boost thinking after a mild head injury

Official title: Retraining neural pathways improves cognitive skills after a mild traumatic brain injury

Funded at Perception Dynamics Institute · NIH-11406497 · Data updated 2026-11-12

A clinical trial tests a brain-training program to improve thinking and memory in people who have had a mild traumatic brain injury (mTBI).

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionPerception Dynamics Institute
NIH-funded
Lab location1 site (Encinitas, UNITED STATES)
Project startJuly 1, 2023
Project endAugust 31, 2029
Funding year2026
Award (this year)$1,005,434
NIH project number2R44NS132718-03
Project IDNIH-11406497 on NIH RePORTER

Who could benefit from this research

Could help

Adults with a mild traumatic brain injury who experience cognitive difficulties.

Less likely to help

Some individuals may not experience meaningful improvement or may not complete the training due to time commitment or other factors.

What this research studies

If you’ve had a mild brain injury, this study aims to see whether a cognitive training program called PATH+DM, delivered over several weeks, can improve visual timing and working memory. Participants will go through different training schedules to find the most effective dose and whether gains last over time. The trial is designed to understand how perceptual and cognitive problems after mTBI respond to targeted mental exercises. Results could help tailor personalized brain-training approaches for people recovering from concussions.

Why it matters

Potential benefit: If successful, participants may experience better memory, attention, and daily functioning after an mTBI.

How similar studies have gone: Previous Phase I results suggested potential benefits from targeted cognitive training, with ongoing research to confirm efficacy.

Where this research is happening

  • Perception Dynamics Institute
    Encinitas, United States
    Active

Researchers

  • Principal investigator: Lawton, Teri a — Perception Dynamics Institute
  • Study coordinator: Lawton, Teri a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.