RESTORE: Re-Engineering Systems to Treat Opioid Use Disorder for Everyone
Official title: Re-Engineering Systems to Treat Opioid use Disorder for Everyone (RESTORE): A Pilot Randomized Controlled Trial
Funded at San Diego State University · NIH-11369218 · Data updated 2026-11-12
A pilot program in California tests a community-engaged approach to making it easier for people with opioid use disorder to get effective treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | San Diego State University NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $1,053,500 |
| NIH project number | 5DP1DA058978-03 |
| Project ID | NIH-11369218 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are individuals with opioid use disorder receiving care in community health clinics in California who are open to integrated, multi-level support.
✕Less likely to help
Patients not seeking OUD treatment or not engaged with the participating clinics may see limited or no direct benefit.
What this research studies
This project partners with community health clinics to test a multilevel intervention that reduces barriers at the patient, provider, and system levels. It uses peer navigators to connect people to buprenorphine and other care while closely studying how feasible and acceptable the approach is in real-world clinic settings. The goal is to gather early signals about what works and what would be needed for a larger, fully powered trial. The work is grounded in implementation science and aims to spread learnings to improve access to treatment across communities.
Why it matters
Potential benefit: If successful, the intervention could make OUD treatment more accessible and acceptable in community clinics, potentially reducing overdose risk and improving health outcomes.
How similar studies have gone: Previous implementation-focused studies suggest that multilevel, community-engaged approaches can improve treatment access, but results vary by setting.
Where this research is happening
-
San Diego State University
San Diego, United States Active
Researchers
- Principal investigator: Smiley, Sabrina Lynn — San Diego State University
- Study coordinator: Smiley, Sabrina Lynn
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.