Improving opioid use disorder treatment for Black individuals.
Official title: Racial Equity in Systems to Treat Opioid Use Disorder for Everyone (RESTORE): A Pilot Randomized Controlled Trial
Funded at San Diego State University · NIH-10917290 · Data updated 2026-11-12
This study is looking at a new way to help non-Hispanic Black individuals get better access to treatment for opioid use disorder, by working with the community to understand their needs and challenges, and seeing how well this approach works in real life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | San Diego State University NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | September 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $1,053,500 |
| NIH project number | 5DP1DA058978-02 |
| Project ID | NIH-10917290 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are non-Hispanic Black individuals who are experiencing opioid use disorder.
✕Less likely to help
Patients who do not identify as non-Hispanic Black or those without opioid use disorder may not benefit from this research.
What this research studies
This research investigates a new intervention aimed at improving access to treatment for non-Hispanic Black individuals suffering from opioid use disorder (OUD). It employs a mixed methods approach, engaging the community to understand their specific needs and barriers to treatment. The study will assess the feasibility and acceptability of this intervention, as well as its preliminary effectiveness in a real-world setting. By focusing on the disparities in treatment access, the research aims to create a scalable model that can be implemented nationwide.
Why it matters
Potential benefit: If successful, this research could significantly improve treatment access and outcomes for Black individuals with opioid use disorder.
How similar studies have gone: Previous research has shown that community-engaged interventions can effectively address health disparities, suggesting potential success for this approach.
Where this research is happening
-
San Diego State University
San Diego, United States Active
Researchers
- Principal investigator: Smiley, Sabrina Lynn — San Diego State University
- Study coordinator: Smiley, Sabrina Lynn
Related research
Other NIH-funded projects on the same topics.
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RESTORE: Re-Engineering Systems to Treat Opioid Use Disorder for Everyone
A pilot program in California tests a community-engaged approach to making it easier for people with opioid use disorder to get effective treatment.
-
Suvorexant to improve sleep in people receiving treatment for opioid use disorder
People on medications for opioid use disorder who have insomnia will be given suvorexant or a placebo to see if it helps their sleep, cravings, and withdrawal symptoms.
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Testing a medication to improve sleep in people with opioid use disorder
This study is looking at whether the sleep medication suvorexant can help people with opioid use disorder who are in long-term treatment by improving their sleep and possibly easing cravings and withdrawal symptoms.
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Using semaglutide to help treat opioid use disorder
This study is looking at whether semaglutide, a medication usually used for diabetes and weight loss, can help people with opioid use disorder feel less cravings and stick with their treatment when they’re also taking buprenorphine.
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Systems analysis to improve opioid use disorder care after jail release (SAIA-MOUD)
A program to help people with opioid use disorder get better, faster, and safer care after they leave jail.
-
Precise epigenetic drugs for opioid addiction
A tiny, targeted drug approach is being developed to help people with opioid use disorder by rewriting the epigenetic signals in the brain to reduce cravings and relapse risk.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.