Reducing stigma and shame to improve HIV care for people with HIV and substance use
Official title: Mitigating the Impact of Stigma and Shame as an Obstacle to Viral Suppression Among People Living with HIV and Substance Use Disorders
Funded at Boston University Medical Campus · NIH-11384200 · Data updated 2026-11-12
A big study tests a supportive program designed to help people living with HIV and substance use disorders stay engaged in care and maintain viral suppression.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston University Medical Campus NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 1, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $740,060 |
| NIH project number | 5R01DA057298-04 |
| Project ID | NIH-11384200 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV who also have a substance use disorder and are engaged in or attempting HIV care.
✕Less likely to help
People without HIV, without substance use disorders, or not engaged in care may not benefit from this intervention.
What this research studies
If you have HIV and a substance use problem, this project tests a program called MATTER that tries to reduce feelings of stigma and shame that get in the way of sticking with treatment. The researchers will compare two groups in a randomized setup to see if MATTER helps people attend appointments, take medications, and keep the virus under control. The study builds on earlier small tests and uses behavioral skills like goal setting and mindful awareness to support health habits. Results could show a practical way to boost viral suppression by addressing emotional and social barriers. The work is conducted at Boston University Medical Campus, led by Abigail Batchelder and team, with real patients contributing to learn what works in real-world care.
Why it matters
Potential benefit: If successful, the intervention could help more people stay adherent to HIV treatment and maintain viral suppression, reducing transmission risk.
How similar studies have gone: Previous pilot testing showed the approach is feasible and acceptable; this study aims to confirm effectiveness in a larger trial.
Where this research is happening
-
Boston University Medical Campus
Boston, United States Active
Researchers
- Principal investigator: Batchelder, Abigail Winston — Boston University Medical Campus
- Study coordinator: Batchelder, Abigail Winston
Related research
Other NIH-funded projects on the same topics.
-
Improving contraception decisions for women with substance use disorders after childbirth
A patient-centered decision tool called MyPath aims to help postpartum women with substance use disorders choose and keep effective contraception after giving birth.
-
Transforming prison care for HIV, HIV risk, and substance use disorders
A patient-friendly look at improving HIV care and prevention for people in state prisons, especially where substance use is common.
-
Genetic factors behind alcohol and opioid use disorders and depression in veterans
A study using genetic data from veterans to understand how genes contribute to co-occurring alcohol use, prescription opioid use, and depression.
-
Written Exposure Therapy for Veterans with PTSD and Substance Use Disorder (brief trauma treatment)
A brief trauma-focused therapy called Written Exposure Therapy is being studied to help veterans who have both PTSD and substance use disorders.
-
Web-based training to treat PTSD and substance use together in Veterans
A web-based training resource helps VA clinicians learn how to provide integrated treatment for Veterans with both PTSD and substance use disorders.
-
Mobile health support to help Veterans with substance use disorders function better after treatment
A smartphone app, based on Motivational Enhancement Therapy, is being developed to help Veterans stay on track and function better after leaving residential substance use treatment.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.