NIH-funded research R01 grant

Reducing stigma and shame to improve HIV care for people with HIV and substance use

Official title: Mitigating the Impact of Stigma and Shame as an Obstacle to Viral Suppression Among People Living with HIV and Substance Use Disorders

Funded at Boston University Medical Campus · NIH-11384200 · Data updated 2026-11-12

A big study tests a supportive program designed to help people living with HIV and substance use disorders stay engaged in care and maintain viral suppression.

More Substance Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus
NIH-funded
Lab location1 site (Boston, United States)
Project startAugust 1, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$740,060
NIH project number5R01DA057298-04
Project IDNIH-11384200 on NIH RePORTER

Who could benefit from this research

Could help

Adults living with HIV who also have a substance use disorder and are engaged in or attempting HIV care.

Less likely to help

People without HIV, without substance use disorders, or not engaged in care may not benefit from this intervention.

What this research studies

If you have HIV and a substance use problem, this project tests a program called MATTER that tries to reduce feelings of stigma and shame that get in the way of sticking with treatment. The researchers will compare two groups in a randomized setup to see if MATTER helps people attend appointments, take medications, and keep the virus under control. The study builds on earlier small tests and uses behavioral skills like goal setting and mindful awareness to support health habits. Results could show a practical way to boost viral suppression by addressing emotional and social barriers. The work is conducted at Boston University Medical Campus, led by Abigail Batchelder and team, with real patients contributing to learn what works in real-world care.

Why it matters

Potential benefit: If successful, the intervention could help more people stay adherent to HIV treatment and maintain viral suppression, reducing transmission risk.

How similar studies have gone: Previous pilot testing showed the approach is feasible and acceptable; this study aims to confirm effectiveness in a larger trial.

Where this research is happening

  • Boston University Medical Campus
    Boston, United States
    Active

Researchers

  • Principal investigator: Batchelder, Abigail Winston — Boston University Medical Campus
  • Study coordinator: Batchelder, Abigail Winston

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.